HSD25 Impact of Clinical Pharmacy Interventions on Health and Economic Outcomes in Type 2 Diabetes: A Systematic Review and Meta-Analysis

There is lack of synthesized evidence on the effectiveness clinical pharmacy interventions outcomes like adverse events (AEs) and mortality, economic diabetes at hospital settings. The aim this study was to examine health patients with type 2 in MEDLINE, EMBASE, PsycInfo, CINAHL, COCHRANE Library were searched from 1990 November 2020. We included randomized controlled non-randomized trials, cohort, before-after studies. Meta-analyses undertaken for Primary glycosylated hemoglobin A1c (HbA1c), all-cause major cardiovascular events, AEs, quality life, outcomes. retrieved 11,853 studies which 44 (n=8623 patients) review. Of these, 29 meta-analyses (n=4055 patients). Clinical significantly reduced HbA1c levels (standardized mean difference (SMD) −0.52, P < 0.001) AEs compared usual care. No eligible reported as One examined mortality no significant between intervention care groups reported. improved costs including medical costs, laboratory tests, cost medications both developed developing countries. showed control, reduction countries has implications improving reducing prevalence medication therapy problems these high. Future trials are warranted establish whether such have an impact